InSpectres
InSpectres is a comedy ghost-busting RPG by Jared Sorensen and published by Memento Mori Theatricks.
The premise is the PCs have a startup supernatural exterminator franchise called InSpectres. Basically, you're the Ghostbusters but with barely any money and no brand recognition. That means no proton packs. You're working on a budget so you gotta go ghetto with weapons built from stuff found at Home Depot. A big part of the game is trying to get your franchise to grow.
PCs hunt more than just ghosts. They also deal with werewolves and vampires and stuff like that. In this world, supernatural things are treated as a nuisance not as insanity-inducing horrors like in Call of Cthulhu. For example, if a mummy comes alive and goes on a rampage at the History Museum's Egyptian exhibit, people treat it like the museum has termites.
InSpectres uses a simple d6 system. It has a built-in pacing mechanic so everyone is aware of how close the session is to ending, kind of like how you know a book is almost about to end because there are only two pages left.
One player can even play as a token supernatural character, just like Slimer from the Ghostbusters cartoon.
[There was a movie made based on the game that came out in 2013.](http://www.imdb.com/title/tt1705111/)