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===Artificial Plague=== The Black Plague killed up to 60% of Europe's population and the Spanish Flu over doubled the death toll of what was then most devastating war in history. With '''''SCIENCE!''''' you could do even better! You could even render your own people immune to the effects before hand and only kill the enemy. Sane people dismiss this as possible but a fantastically stupid idea because viruses are impossible to contain and like to mutate, rendering any vaccine you used worthless. Still, people interested in causing the end of the world have minimal overlap with sane people, so terrorists causing one is a popular plot. Another possibility is a virus in a research lab breaking containment rather than being released intentionally. However before you start panicky a plague basically has no chance at killing humanity off. It can do a lot of damage yes, but once it kills enough people it will, like a fire, run out of fuel and burn it self out. This is why the common cold is so, well, common, It doesn't kill you so you can keep spreading it. Any sickness lethal enough to even have a shot at killing humanity off, will kill people so fast that it can't spread, even assuming humans can't treat it. Now if you think the COVID-19 pandemic showed that developing a vaccine isn't necessarily quick or easy, well your wrong. Less then a year for a vaccine is incredibly quick all things considered. In contrast the polio vaccine took over 4 years to produce. And after almost less then a year we are managing to produce over [[Noblebright|1 Million Doses Per of Vaccine per-day]]. That is a feat and a half even before you consider how we've managed to mitigate it via social behavior.
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