AIDS

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AIDS is a horrible and deadly virus which you can get by fucking like there's no tomorrow. It also spreads by shooting up. In 40k, it is spread by Slaanesh after it was made by Nurgle, who gave it to Slaanesh as a gift.

It is God's way of saying; "Fuck you." IRL. AIDS is a clever acronym meaning 'Anally Inflicted Death Sentence.'