Macho Women With Guns

A satirical comedy RPG created in the 1980s by a small-time RPG company called Blacksburg Tactical Research Center. It's a femsploitation game, in which the PCs are big-breasted warrior-women running around in a post-apocalyptic hellhole where women have become the action-gal, take-charge heroines and men tend to be either spineless arm-candy or misogynystic stereotypes. It doesn't take itself seriously at all and is pretty much designed for jokey, sex-flavored beer 'n' pretzel type gaming.

What else can you say about a game where bimbo succubi fighting leather-clad bike-riding nuns is normal and tit size is an important ability score?

The most recent version is a D20 Modern spin-off/update/revamp by Mongoose Publishing, which consists of a corebook, two adventures (Adolf Hitler - Porn Star, and The Sex Presidents), and a "diet edition" (trimmed down version of the corebook).