XCOM

X-Com is a series of PC games. The focus is strategic squad action... Against aliens. One way or another, squad members will die horribly, no matter how carefully you try; shot in the back by a mind-controlled buddy, shot in the back with a stray shot from your buddy, shot in the back by a Sectoid hiding in the dark, too close to an exploding Cyberdisk, zombified by your buddy who was actually a Chrysallid...

The game is in isometric view and old; which makes it /tg/ material more than anything else.