Broodlord
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A Broodlord is basically a souped-up psychic genestealer. Previously an HQ choice, the 5th edition codex made it into a genestealer sergeant. Though absolutely rape-tastic in assault, their BS of 0 means they can't use any psychic shooting powers, which makes their Psyker status less useful. However, being a sergeant makes this loss a bit insignificant considering that he'll be covered by bodies, allowing him to make sure his targets die once he gets there.
Space Hulk, having been made before the gimping influence of the Cruddace, allows the Broodlord to become more ruthless thanks to the lack of wounds, making the likelihood of killing it very small (like rolling 5+'s on both die kind of small). However, this being Space Hulk, everything can kill your Termies.